ImmunoGen, Oxford BioTherapeutics To Collaborate To Develop Novel Antibody-Drug Conjugates

RTTNews | 1047天前
ImmunoGen, Oxford BioTherapeutics To Collaborate To Develop Novel Antibody-Drug Conjugates

(RTTNews) - ImmunoGen Inc. (IMGN), a developer of antibody-drug conjugates (ADCs) for the treatment of cancer, announced Monday a multi-year collaboration to research novel, first-in-class ADCs with clinical stage oncology company Oxford BioTherapeutics (OBT), utilizing ImmunoGen's proprietary linker-payload technology directed to novel targets identified via OBT's proprietary OGAP discovery platform.

The companies will support these research and development (R&D) efforts through joint funding and by using their respective proprietary technologies.

As part of the agreement, OBT will receive an upfront payment from ImmunoGen, reflecting OBT's preclinical programs to be included in the collaboration. After antibodies generated by OBT have been coupled with ImmunoGen's proprietary linker-payload technology, each company will have the opportunity to select one or more development programs to further develop on its own.

Once a company has chosen a given program, it will be solely responsible for all R&D costs associated with that specific program.

Each company will be eligible to receive milestone payments based on the achievement of pre-specified development and regulatory milestones, as well as tiered royalties as a percentage of worldwide commercial sales, with respect to each program selected by the other company.

read more
Bay Street May Open On Weak Note

Bay Street May Open On Weak Note

Canadian shares look headed for a weak start on Friday, weighed down by lower crude oil and metal prices. Worries about U.S. - China trade tensions may also weigh on sentiment.
RTTNews | 37分钟前
Colgate-Palmolive Q1 Beats Market; Cuts FY25 Earnings, Organic Sales View On Tariffs

Colgate-Palmolive Q1 Beats Market; Cuts FY25 Earnings, Organic Sales View On Tariffs

Consumer products major Colgate-Palmolive Co. on Friday reported higher profit above market estimates in its first quarter with organic sales growth amid very difficult market conditions. Net sales, meanwhile declined, though were above the Street. Further, the firm trimmed its earnings and organic sales forecast for fiscal 2025 on tariff uncertainty, but raised net sales view.
RTTNews | 58分钟前
FTSE 100 Up Slightly In Cautious Trade

FTSE 100 Up Slightly In Cautious Trade

U.K. stocks are turning in a mixed performance in cautious trade on Friday with investors digesting some earnings updates, and hoping for a de-escalation in U.S. - China trade spat.
RTTNews | 1小时32分钟前
CAC Modestly Higher; Safran Rises Sharply On Strong Results

CAC Modestly Higher; Safran Rises Sharply On Strong Results

French stocks are gaining some ground in positive territory on Friday amid optimism about a likely de-escalation in U.S.-China trade dispute, and on data showing an improvement in French manufacturing sentiment in the month of April.
RTTNews | 2小时24分钟前
Yen Falls As European Shares Inch Higher

Yen Falls As European Shares Inch Higher

The Japanese yen weakened against other major currencies in the European session on Friday, as European shares eked out modest gains, with signs of easing Sino-U.S. trade tensions and some upbeat corporate earnings helping underpin investor sentiment.
RTTNews | 2小时55分钟前